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A master’s thesis Viva

A master’s thesis was discussed at the Faculty of Medicine / University of Kufa, Ali Salman Jawad Al-Rammahi, the student from department of pharmacology and therapeutics tagged his thesis as (The potential protective effect of liraglutide and empagliflozin from acute renal injury during endotoxemia in non-diabetic mice). The aim of the study was to investigate the potential protective effect of liraglutide and empagliflozin from acute renal injury during endotoxemia in non-diabetic mice. The results showed that blood levels of urea and serum creatinine and tissue levels of TNF-α, IL-6, IL-10 and TNFR1 in the sham  group had significantly lower than those in the sepsis and vehicle groups. In addition, it indicated that the blood levels of urea, serum creatinine and tissue levels of TNFα, IL-10, IL-6, and TNFR1 in empagliflozin and liraglutide were significantly lower than those of the sepsis and vehicle groups otherwise IL-10 was significantly increased in empagliflozin and liraglutide comparing with sepsis and vehicle groups  .

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